A Comparison in the Analysis of Volatile and Semi-volatile Organic Compounds in Oral Rinse vs Whole Breath Sampling using Vacuum Assisted Sorbent Extraction and GC-MS
Authors: Sage J. B. Dunham, Victoria L. Noad, Bailey S. Arakelian & Daniel B. Cardin Introduction Compositional analysis of products, including any contaminants present, from raw materials to finished products is crucial to ensure quality and safety. Headspace Sorbent Pens (HSPs) are used with the technique, Vacuum Assisted Sorbent Extraction (VASE), to extract volatile organic […]
Authors: María J. Trujillo-Rodríguez, Jared L. Anderson, Sage J. B. Dunham, Victoria L. Noad & Daniel B. Cardin Abstract Vacuum-assisted sorbent extraction (VASE) has been applied in combination with gas chromatography-mass spectrometry for the determination of UV filters in water samples. VASE is a variant of headspace extractionwhich was developed in conjunction with the sorbent […]
Authors: Sage J. B. Dunham, Victoria L. Noad, Bailey S. Arakelian & Daniel B. Cardin Overview A solvent free headspace extraction approach – vacuum assisted sorbent extraction (VASE) – is applied in combination with thermal desorption (TD)-gas chromatography-mass spectrometry (GC-MS) to examine the chemical composition of cannabis and cannabis infused consumer products. Application of VASE […]
Authors: Sage J. B. Dunham, Victoria L. Noad, Bailey S. Arakelian & Daniel B. Cardin Overview The specific chemical composition of cannabis is responsible for the fragrance and flavor of the product, the experience of a recreational high, and the medicinal benefit. In a phenomenon known as the “entourage effect”, evidence further suggests that compounds […]
Authors: Sage J. B. Dunham, Victoria L. Noad, Bailey S. Arakelian & Daniel B. Cardin Overview Current analytical methods for evaluating volatile and semi volatile organic compounds (VOCs & SVOCs) in water often require large sample volumes (1 L or more), are labor intensive, and rely upon liquid-liquid extraction into organic solvents. Here we present a sensitive, […]
Authors: Sage J. B. Dunham, Victoria L. Noad, Bailey S. Arakelian & Daniel B. Cardin Overview In the 30 years since the invention of solid phase microextraction (Belardi & Pawliszyn, 1989), headspace (HS) extraction has developed into a powerful family of techniques for both targeted and untargeted chemical analysis of volatile and semi volatile compounds. We recently developed […]
Authors: Victoria L. Noad, Sage J. B. Dunham, and Daniel B. Cardin Overview • A new instrument design and methodology for trace-level headspace analysis of polycyclic aromatic hydrocarbons (PAHs) is described. • Using a 1 mL sample of water, quantitation from 5 ppt – 10 ppb is demonstrated for a wide range of polycyclic aromatic hydrocarbons […]
Authors: Victoria L. Noad, Sage J. B. Dunham, and Daniel B. Cardin Overview Due to recent legislative changes, consumption of cannabis products are becoming accepted as a medical treatment and a mainstream recreational product worldwide including many US states and Canada. Reliable analytical methods are critical to ensuring consistent dosing, efficacy, and safety. Current techniques […]
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