Compare All Sorbent Pen Extraction Techniques For Complete Coverage of VOC to SVOC Analysis Of Virtually Any Matrix
Definitions:
Open System - Unretained compounds/gases allowed to pass through sorbent for removal by pump/vacuum.
Closed System - Completely isolated during extraction, so breakthrough of even the lightest compounds isn't possible. Allows recovery of wider boiling point range.
Introducing LVSH6 - What is it
The LVSH6 solution from Entech is a next generation Large Volume Static Headspace (LVSH) technique that uses the SPR40 autosampler to carefully and quantitatively transfer the equilibrated headspace above a liquid or solid sample through an ASP Sorbent Pen in order to measure the composition of the equilibrated headspace. This equilibrated headspace is what a consumer experiences when they open a container of facial cream, or open a food package, or even when they apply a fragrance to their skin. Virtually all other headspace techniques perform extractions, leaving the fixed gases behind (air, nitrogen, etc), or they add more fixed gases to the headspace to flush compounds to an external sorbent, but in both cases the equilibrium is disturbed which ends up providing a compositional analysis of the liquid or solid sample, not what a consumer would be smelling. Stated another way, if a SPME extraction of a typical 10mL vial were to be performed over a 10-20 minute period to try to improve the sensitivity of the method, and then this fiber were desorbed into another inert container so that all compounds would be in the gas phase, the resulting aroma will almost certainly be different than what was present in the original, equilibrated headspace. As long as headspace is pulled from the container without being replaced by additional gases, the equilibrium that has been set up at a given temperature will not be affected very much, especially if we only collect about half of the volume of the vial. With a 1L vial where 900cc is headspace, that would be 450-500cc of fully equilibrated headspace, and when using a splitless injection technique, this could provide low to even sub part per trillion detection limits on some GCMS analyzers. This provides aroma/flavor/fragrance chemists with a whole new approach for “seeing what their customers are smelling”. Knowing the composition in the liquid or solid is only half the challenge. Unless the partition coefficient for each compounds in each matrix is known ( an near impossible task), the headspace at equilibrium must also be determined experimentally. That is what LVSH offers. Therefore, VASE to measure the composition of the liquid or solid samples, and LVSH to measure the equilibrated headspace concentrations. The LVSH6 module along with the volume measurement capabilities of the SPR-FM add on module makes the entire process automated for six 1L vials.
LVSH - Technique Selection Guide
Sample Type: Liquids/Solids/Consumer Products
Extraction Temperatures: 30° – 60° C
Operational Mode: Large Volume Static Headspace
BP Range: -50° C to >450° C
Vial Sizes: 1Liter
Typical Mode: Split, Splitless VOC Thru SVOC
Water Management: Hydrophobic Media, Split injection

The LVSH6 allows 4 different modes of operation, providing maximum flexibility for trace level equilibrated headspace analysis
Mode 1: Non-Heated, Fully Static LVSH
LVSH jars with ASP Pens are placed into the 6 position tray, and a volume from 10 – 500 cc of headspace are slowly drawn through each ASP Pen. Pens are isolated for GCMS analysis
Mode 2: Heated, Fully Static LVS
LVSH jars with ASP Pens are placed into the LVSH6 tray, and a transport tool is used to move the vials to a heated oven for a period of time, followed by drawing 10-500cc of headspace through the ASP Pens. Pens are isolated for GCMS Analysis
Mode 3: Vacuum Equilibration / N2 Pulsed LVSH
LVSH jars with sample and ASP Pens are placed into a freezer to minimize volatiles presence in the headspace, then the headspace is evacuated through a separate port in the lid, followed by placement of samples under vacuum in the LVSH6 tray. Vial assemblies are moved to the heater for vacuum equilibration where equilibration will be reached far faster under vacuum than at atmospheric pressure. Afterwards, samples are pressurized with UHP Nitrogen, followed by ASP extraction of 10-500cc of sample. Pens are isolated for GCMS analysis.
Mode 4: Vacuum Equilibration / X-LVSH Extraction
Extremely Large Volume Static Headspace (X-LVSH). Similar to Mode 3, except the UHP N2 Fill Tool remains connected to the sample vial during very slow sampling through the ASP, so N2 enters at the same rate as the flow through the ASP (2-10cc/min). N2 is introduced near the bottom of the vial, while ASP samples near the top, so introduced N2 has time to fully equilibrate with the headspace prior to collection through ASP. Sample volumes 100-2000cc.
LVSH6 Modules
LVSH6 Kits
Image (click to enlarge) | Part # | Description | Unit | link to product |
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SP-HS-V1L | 1L Vial + Lid/Cap/Seal for Sorbent Pen Extraction | EA |
LVHS6 Vials
Image (click to enlarge) | Part # | Description | Unit | link to product |
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39-75500W | 500mL LVSH6 Vial Caps not included | 12pk | |
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39-76850HS | Vial Caps for 500mL vials (high temp) | 12pk | Product Page |
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HS-76050 | Silonite™ Liners for 500mL vials | 12pk | Product Page |
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39-75L1W | 1L LVSH6 Vials | 12pk | Product Page |
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39-76894HS | Vials Caps for 1L vials (high temp) | 12pk | Product Page |
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HS-761000 | Silonite™ Liners for 1L vials | 12pk | Product Page |
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SP-L100S | Lid Bushing Sorbent Pen Interface | 12pk | Product Page |
Extraction Controller
Image (click to enlarge) | Part # | Description | Unit | link to product |
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SPR-EMC-VASE | Controls MA-VASE10, 3700, and LVSH6 modules, 120VAC/60Hz | EA | ||
SPR-EMC-VASE-HV | Controls MA-VASE10, 3700, and LVSH6 modules, 240VAC/50Hz | EA |

Compare All Sorbent Pen Extraction Techniques For Complete Coverage of VOC to SVOC Analysis Of Virtually Any Matrix




