The all-new 7650HS-CTS is the only commercially available solution that can quantify the consumer experience by taking an equilibrium “snapshot” of the headspace to accurately determine its composition from the lightest through the heaviest compounds. The 7650HS-CTS is truly unique as it is the industries “only” system that uses multiple stages of true capillary columns to perform headspace preconcentration. This patent pending technology is creating a SPME like sampling, but in a way that obtains complete recovery of the lightest to the heaviest headspace compounds with virtually no reactive losses and no carryover.
The 7650HS-CTS supports sample analysis via large and small volume static headspace (1–1000cc) to accommodate a wide range of concentrations with quantitative recovery of compounds with boiling points from -50°C to >400°C. The 7650HS-CTS maximizes throughput while offering state-of-the-art performance in quantitative accuracy, sensitivity, and low carryover. The 7650HS-CTS resides to the right of the GCMS system, with multiple trays supporting several different sample container sizes. The 7650HS-CTS is compatible with the latest 1D/2D chromatographic solutions for food, flavor, aroma, product testing, environmental, and clinical applications.
Classical SPME (Solid Phase Microextraction) uses passive diffusion to collect and partition headspace compounds onto a coated fiber/lament placed directly in the sample headspace. The time required for each analyte to come to equilibrium with a SPME fiber depends on individual vapor pressures and coating affinities. Lighter, more volatile compounds have much less phase affinity than heavier compounds. As a result, true headspace concentrations fail to be accurately analyzed and reported whenever the SPME fiber headspace exposures exceed the equilibration time of the most volatile analytes – which may occur in just a few seconds!Read More
Unfortunately, it can take 10–90 minutes to collect enough of the heavier aroma compounds to allow detection by GCMS. This results in the heavier compounds being over-represented relative to lighter compounds by several hundred fold. This fact alone makes passive SPME a qualitative, rather than a quantitative technique for the determination of headspace composition. In addition, the extent of partitioning into a SPME fiber for any particular analyte is dependent on temperature and sample matrix variations. Upon desorption, the SPME lament is placed directly into a hot injector – which may thermally alter the sample composition. Capillary Column Trapping with the 7650HS-CTS utilizes multiple capillary columns with increasing strength to recover all relevant compounds, allowing a known volume to be sampled for quantitative determination of headspace composition. Water and air pass through the traps almost unretained, eliminating the interferences associated with improper management of the matrix.
The 7650HS-CTS performs Large Volume Static Headspace under equilibrium conditions. Samples are allowed to come to equilibrium over 30-60 minutes, with optional warming in a mixing oven prior to extracting the headspace into the capillary traps. Aroma Significant Compounds (ASC), are easily identified with a small volume injection (10cc) using GC/Olfactometry. The mass spectrum of detected aromas can then be obtained by analyzing a larger volume of headspace (50–1000cc). Only those aromas detected within the small volume GC/O analysis need be identified, significantly reducing aroma characterization complexity. High ethanol concentrations are managed either by flushing additional gas through the column traps in the forward flow direction, or by using a solvent delay in the mass spectrometer to let the ethanol clear the GC column prior to commencing with data collection.
Direct Capillary Column Trapping
Capillary columns perform the sample enrichment, improving quantitative accuracy.
Sample Vial Sizes from 20 to 1000cc
Optimal sensitivity and statistical accuracy
Micro-QT Septumless Sample Interface
Gas-tight seal down to full vacuum.
Heat Samples from Ambient to 100°C
Recovers Thermally Labile Compounds
Analyze compounds containing sulfur, phosphorous, nitrogen.
Extremely Low Carryover
Capillary column traps have far less carryover relative to packed traps
Supports All Balance Gas Compositions
(Air, nitrogen, CO2 , H2 , He, methane, mixture).
Easily Handles High Ethanol Matrices
Sample from 1 to 1000cc
Maximize GCMS dynamic range.
Liquid Nitrogen Focuser
Improves separation and the resolution of compounds boiling below 50°C.
Mixing and Agitating Oven
Rapid heating and sample equilibration.
Advanced Water Management
Capillary column traps have virtually zero water retention.
Headspace extraction is performed using Entech’s unique septumless micro-seal for repeated gas-tight sample access. This approach completely avoids the use of septa, preventing coring and compound absorption found with these simple rubber seals. The micro-seal allows samples to be stored under vacuum for enhanced equilibration rates.
The most advanced and quantitative high sensitivity static headspace solution available. It traps all compounds boiling from -50°C to >400°C, except for water vapor which is almost unretained. Thermally labile, GC compatible compounds are virtually all recovered, because the headspace goes directly to capillary column traps, followed by backflushing right onto the GC analytical column.
|7650HS-CTS Bundle (120VAC/60Hz)*||7650HS-CTS-B01||1|
|11 Position 500mL Wide-Mouth LVSH Tray HS-ST280-011||HS-ST280-011||1|
|10 Position 1L Wide-Mouth LVSH Tray||HS-LT384-010||1|
|500mL LVSH Vials (box of 12)||39-75500W||1|
|Vial Caps for 500mL vials (high temp)||39-76850HS||12|
|Silonite™ Liners for 500mL vials||HS-760500||12|
|1L LVSH Vials (box of 12)||39-75L1W||1|
|Vials Caps for 1L vials (high temp)||39-76894HS||12|
|Silonite™ Liners for 1L vials||HS-761000||12|
|*Use part #7650HS-CTS-HV-B01 for 220-240VAC/50Hz|
The 7650-HS uses Entech’s exclusive Multi-Capillary column trapping system (MCCTS) that provides better “true” characterization of trace headspace concentrations than any other headspace technique. A 3-stage trapping system features an initial thick-film GC column that performs On-Column Extraction to “absorb” semi-volatile compounds, allowing them to be simply “reverse flushed” off the thick-film column and onto the analytical column in the GC for better recovery of both high boilers and thermally labile compounds.